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抗体 > 一抗 > 转录因子NAC1抗体
产品名称:
转录因子NAC1抗体
型号:
CS-A2007
生产地址
进口、国产
产品价格
电议
产品简介
可为客户提供抗体标记、抗体对筛选、免疫学检测等增值服务。
产品详情

一、概述:

产品属性:
中文名称  转录因子NAC1抗体 
英文名称   Anti-NAC1/BTBD14B
规 格 0.2ml/200μg 
浓    度 1mg/1ml 
价格 来电可享受优惠
英文名称  Anti-NAC1/BTBD14B
中文名称  转录因子NAC1抗体
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep
产品类型 一抗
研究领域 肿瘤 发育生物学 干细胞 转录调节因子
蛋白分子量 predicted molecular weight: 57kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human NAC1/BTBD14B (311-400aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
抗体基本结构:



别 名 BEND8; BTB Domain Containing 14B; BTB/POZ domain-containing protein 14B; btbd14b; btbd14b; FLJ37383; NAC-1; NAC1; Nacc1; NACC1_HUMAN; Nucleus accumbens-associated protein 1.
产品介绍 NAC1 is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. 

标签:抗体 

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