产品属性：

商品介绍：

英文名称WT1 Recombinant Rabbit mAb

中文名称肾母细胞瘤蛋白重组兔单抗

别    名WT1_HUMAN; Wilms tumor protein; WT33; WT1 transcription factor; GUD; AWT1; WAGR; WT-1; WT33; NPHS4; WIT-2;  

抗体来源Rabbit

克隆类型Recombinant

克 隆 号7C5

交叉反应Human,Mouse

产品应用WB=1:500-2000,IHC-P=1:500-1000,IHC-F=1:500-1000,IF=1:500-1000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量55 kDa

检测分子量

细胞定位细胞核 细胞浆

性    状Liquid

浓    度1mg/ml

免 疫 原A synthesized peptide derived from human WT1: 60-250/449

亚    型IgG

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
WT1 Recombinant Rabbit mAb产品介绍Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.