产品属性：

商品介绍：

英文名称MAPT/Tau Mouse mAb

中文名称微管相关蛋白MAPT/Tau单克隆抗体

别    名TAU_HUMAN; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau (PHF-tau); MAPTL; MTBT1; TAU; Tau-F; Tau-4; FTD1; MSTD; PPND; DDPAC; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6;  

研究领域细胞生物  免疫学  神经生物学  信号转导  

抗体来源Mouse

克隆类型Monoclonal

克 隆 号6E2

交叉反应Human,Mouse,Rat

产品应用WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量46/79 kDa

检测分子量

性    状Liquid

浓    度1mg/ml

免 疫 原Recombinant Human Tau-4 Protein: 1-441/441

亚    型IgG3

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
MAPT/Tau Mouse mAb产品介绍Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.