英文名称NME1/NM23A Rabbit pAb

中文名称肿瘤转移抑制基因抗体

别    名NDKA_HUMAN; Nucleoside diphosphate kinase A; EC:2.7.4.6; NDK A; NDP kinase A; Granzyme A-activated DNase(GAAD); Metastasis inhibition factor nm23; NM23-H1; Tumor metastatic process-associated protein; NME/NM23 nucleoside diphosphate kinase 1; NDPKA; NM23; NB; AWD; NBS; GAAD; NDKA; NDPK-A;  

研究领域肿瘤  

抗体来源Rabbit

克隆类型Polyclonal

克 隆 号

交叉反应Human,Mouse,Rat

产品应用WB=1:500 - 1:1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量17 kDa

检测分子量

细胞定位细胞核 细胞浆

性    状Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Nm23: 51-152/152

亚    型IgG

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
NME1/NM23A Rabbit pAb产品介绍This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.