产品属性：

商品介绍：

英文名称Ki-67 Recombinant Rabbit mAb

中文名称Ki67重组兔单抗

别    名Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_HUMAN.  

研究领域肿瘤  细胞生物  神经生物学  细胞周期蛋白  细胞分化  细胞类型标志物  表观遗传学  

抗体来源Rabbit

克隆类型Recombinant

克 隆 号D9H1

交叉反应Human,Mouse,Rat

产品应用WB=1:1000-5000,IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000,Flow-Cyt=1:100-200,ICC/IF=1:200-1000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量358 kDa

检测分子量

细胞定位细胞核 

性    状Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Ki67 

亚    型IgG

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed

Ki-67 Recombinant Rabbit mAb产品介绍Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.