产品属性：

商品介绍：

英文名称Human IgM Recombinant Rabbit mAb

中文名称人IgM重组兔单抗

别    名human Immunoglobulin M  

抗体来源Rabbit

克隆类型Recombinant

克 隆 号4C2

交叉反应Human

产品应用WB=1:1000-5000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:100-500

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量900 kDa

检测分子量

细胞定位分泌型蛋白 

性    状Liquid

浓    度1mg/ml

免 疫 原Human IgM 

亚    型IgG

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antib

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed

Human IgM Recombinant Rabbit mAb产品介绍IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.