产品属性：

商品介绍：

英文名称Granzyme B Mouse mAb

中文名称颗粒酶B单克隆抗体

别    名GranzymeB; Granzyme-B; C11; Cathepsin G-like 1; CTLA-1; Cathespin G Like 1; CCPI; CCP-1; CGL 1; CGL1; CSP B; CSPB; CTLA 1; CTLA1; CTSGL 1; CTSGL1; Cytotoxic serine protease B; Cytotoxic T Lymphocyte Associated Serine Esterase 1; Cytotoxic T lymphocyte proteinase 2; Fragmentin 2; Fragmentin2; Granzyme 2; Granzyme2; GRB; GZMB; Cytotoxic T-lymphocyte proteinase 2; Fragmentin-2; GRAB_HUMAN; Granzyme B(granzyme 2, cytotoxic T lymphocyte associated serine esterase 1); Granzyme B; Granzyme-2; GranzymeB; HLP; T cell serine protease 1 3E; T cell serine protease 1-3E; T-cell serine protease 1-3E; HLP; Human lymphocyte protein; Lymphocyte protease; Protease Serine B; SECT; AA 18-29; T cell serine protease 1.  

研究领域肿瘤  细胞生物  免疫学  细胞凋亡  t-淋巴细胞  

抗体来源Mouse

克隆类型Monoclonal

克 隆 号3A10

交叉反应Human

产品应用IHC-P=1:200-1000,IHC-F=1:200-1000,IF=1:200-1000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量25 kDa

检测分子量

细胞定位细胞外基质 分泌型蛋白

性    状Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human Granzyme B

亚    型IgG

纯化方法affinity purified by Protein A

缓 冲 液0.02% Proclin300, 0.5% BSA, 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
Granzyme B Mouse mAb产品介绍

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]