产品属性：

商品介绍：

英文名称CK10/Cytokeratin 10 Recombinant Rabbit mAb

中文名称细胞角蛋白10重组兔单抗

别    名type I cytoskeletal 10; BCIE; BIE; CK 10; CK-10; ck10; Cytokeratin 10; Cytokeratin-10; Cytokeratin10; EHK; k10; K1C10_HUMAN; Keratin 10; Keratin; Keratin type i cytoskeletal 10; Keratin type I cytoskeletal 59 kDa; Keratin-10; Keratin10; kpp; Krt 10; KRT10; krt10; Keratin, type I cytoskeletal 10.  

研究领域信号转导  细胞骨架  细胞外基质  

抗体来源Rabbit

克隆类型Recombinant

克 隆 号1D8

交叉反应Human,Mouse,Rat

产品应用WB=1:1000-10000,IHC-P=1:1000-5000,IHC-F=1:1000-5000,IF=1:1000-5000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量59 kDa

检测分子量

细胞定位细胞浆

性    状Liquid

浓    度1mg/ml

免 疫 原A synthesized peptide derived from human Cytokeratin 10: 550-584

亚    型IgG

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
CK10/Cytokeratin 10 Recombinant Rabbit mAb产品介绍Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.