产品属性：

商品介绍：

英文名称CD105 Mouse mAb

中文名称CD105抗体

别    名END; Endoglin; ENG; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15.2; CD 105; CD105 antigen; EGLN_HUMAN; AI528660; AI662476; S-endoglin; SN6.  

研究领域肿瘤  心血管  细胞生物  免疫学  信号转导  干细胞  细胞膜受体  细胞表面分子  血管内皮细胞  

抗体来源Mouse

克隆类型Monoclonal

克 隆 号1E9

交叉反应Human

产品应用IHC-P=1:200-2000,IHC-F=1:200-2000,IF=1:200-2000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量70 kDa

检测分子量

细胞定位细胞膜

性    状Liquid

浓    度1mg/ml

免 疫 原Recombinant human CD105 : 26-586/658 (C-6x His-Tag)

亚    型IgG1

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
CD105 Mouse mAb产品介绍This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]