产品属性：

商品介绍：

英文名称Calreticulin Mouse mAb

中文名称钙网蛋白单克隆抗体

别    名Autoantigen RO; CALR; CALR protein; CALR_HUMAN; cC1qR; CRP55; CRTC; Endoplasmic reticulum resident protein 60; ERp60; grp60; HACBP; RO; Sicca syndrome antigen A; SSA.  

研究领域肿瘤  信号转导  细胞类型标志物  肿瘤细胞生物标志物  新陈代谢  

抗体来源Mouse

克隆类型Monoclonal

克 隆 号G3F7

交叉反应Human,Mouse,Rat

产品应用WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:400-800,IF=1:100-500

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量44 kDa

检测分子量

细胞定位细胞浆 细胞膜 细胞外基质 分泌型蛋白

性    状Liquid

浓    度1mg/ml

免 疫 原Recombinant human CALR.

亚    型IgG1, k

纯化方法affinity purified by Protein G

缓 冲 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
Calreticulin Mouse mAb产品介绍Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]