产品属性：

商品介绍：

英文名称beta-Amyloid(1-42) Mouse mAb

中文名称β淀粉样肽（1-42）单克隆抗体

别    名beta-Amyloid(1-42); A4; AAA; ABETA; ABPP; AD1; Alzheimers Disease Amyloid Protein; Amyloid B; Amyloid beta A4 Protein Precursor; Amyloid beta; Amyloid of Aging and Alzheimer Disease; APP; APPI; B Amyloid; beta APP; Cerebral Vascular Amyloid Peptide; CTFgamma; CVAP; PN II; PN2; PreA4; Protease nexin II; A beta; Amyloid 1-42.  

研究领域细胞生物  免疫学  神经生物学  Alzheimer's  

抗体来源Mouse

克隆类型Monoclonal

克 隆 号6C8

交叉反应Human (predicted: Mouse,Rat)

产品应用WB=1:500-2000,IHC-P=1:500-5000,IHC-F=1:500-5000,IF=1:200-5000

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

理论分子量4.4 kDa

检测分子量

细胞定位细胞核 细胞浆 细胞膜 细胞外基质

性    状Liquid

浓    度1mg/ml

免 疫 原KLH conjugated synthetic peptide derived from human beta-Amyloid(1-42): 672-713/770 or 1-42/42

亚    型IgG2b

纯化方法affinity purified by Protein A

缓 冲 液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PubMedPubMed
beta-Amyloid(1-42) Mouse mAb产品介绍The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.