化学性质:
规格 | 5mg 10mg 25mg 50mg |
CAS | 329196-48-7 |
别名 | N/A |
化学名 | N-[3-(1H-benzimidazol-2-yl)-4-chlorophenyl]-3,4,5-triethoxybenzamide |
分子式 | C26H26ClN3O4 |
分子量 | 479.96 |
溶解度 | 30mg/mL in DMSO, or in DMF |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
SANT-2 is a Smoothened (Smo) receptor antagonist.[1],[2] It binds to the Smo receptor (Kd = 12 nM) and inhibits binding of the Smo receptor agonist SAG-1.3 and antagonist cyclopamine(Kis = 7.8 and 8.4 nM, respectively). SANT-2 inhibits hedgehog signaling induced by an N-terminal fragment of sonic hedgehog (Shh) in an Shh-LIGHT2 cellular assay (IC50 = 30 nM).[1]
特别提醒:
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2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
标签:SANT-2
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