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Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.[1] It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients.[2] It also has growth-inhibitory activity on tumor cells; the IC50 value for the inhibition of human ovarian cancer is 7.5 μM.[3]

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