上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10 mg 25 mg 50 mg 100 mg |
| CAS | 61445-55-4 |
| 别名 | N/A |
| 化学名 | N/A |
| 分子式 | C5H10N2O3 |
| 分子量 | 146.1 |
| 溶解度 | DMF: 30mg/mL,DMF:PBS (pH 7.2) (1:7): 0.12mg/mL,DMSO: 20mg/mL,Ethanol: 25mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a tobacco-specific nitrosamine carcinogen.1 It is oxidized to the reactive metabolite methyl-2-oxopropylnitrosamine (MOPN) in isolated rat liver mitochondria.2 NMBA induces bladder transitional cell carcinomas in rats when administered in the drinking water at a concentration of 300 mg/L per day.3
1.Djordjevic, M.V., Brunnemann, K.D., and Hoffmann, D.Identification and analysis of a nicotine-derived N-nitrosamino acid and other nitrosamino acids in tobaccoCarcinogenesis10(9)1725-1731(1989) 2.Janzowski, C., Landsiedel, R., G?lzer, P., et al.Mitochondrial formation of β-oxopropyl metabolites from bladder carcinogenic ω-carboxyalkylnitrosaminesChem. Biol. Interact.90(1)23-33(1994) 3.Lijinsky, W., Reuber, M.D., Saavedra, J.E., et al.Carcinogenesis in F344 rats by N-nitrosomethyl-n-propylamine derivativesJ. Natl. Cancer Inst.70(5)959-963(1983)
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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