R-(+)-Mono-desmethylsibutramineCS-01Y78556_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	5 mg 10 mg
CAS	229639-54-7
别名	N/A
化学名	N/A
分子式	C16H24ClN
分子量	265.82
溶解度	N/A
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

R-(+)-Mono-desmethylsibutramine is the R enantiomer of Mono-desmethylsibutramine.

Sibutramine, a monoamine reuptake inhibitor, is used as a racemate, for the treatment of obesity. It is converted in vivo mainly to two desmethyl active metabolites, mono-desmethylsibutramine (MDS) and di-desmethylsibutramine (DDS) [1].

[1]. Bae K, et al. Analysis of enantiomers of sibutramine and its metabolites in rat plasma by liquid chromatography-mass spectrometry using a chiral stationary-phase column. J Pharm Biomed Anal. 2009 Sep 8;50(2):267-70.

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标签：R-(+)-Mono-desmethylsibutramine

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