化学性质:
规格 | 500 µg 1 mg 5 mg |
CAS | N/A |
别名 | N/A |
化学名 | N/A |
分子式 | C46H64N14O12S2 • XCF3COOH |
分子量 | 1069.2 |
溶解度 | DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 2 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at human vasopressin V1a, V1b, and V2 receptors with Ki values of 62.4, 5.8, and 23.3 nM, respectively.1
1.Cheng, L.L., Stoev, S., Manning, M., et al.Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4J. Med. Chem.47(9)2375-2388(2004)
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