化学性质:
规格 | 5mg 25mg |
CAS | 156727-74-1 |
别名 | NIH 10815 |
化学名 | 4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide |
分子式 | C28H39N3O2 |
分子量 | 449.64 |
溶解度 | 0.2 mg/ml in DMSO, 0.2 mg/ml in DMF |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
SNC 80 is a selective nonpeptide agonist of the δ-opioid receptor (Ki = 0.18 nM, IC50 = 2.73 nM) that is over 2,000-fold less effective at the μ-opioid receptor.[1],[2],[3] It effectively activates µ/δ receptor heteromers (EC50 = 52.8 nM) but not κ/δ or μ/κ heteromers.[4] SNC 80 has antinociceptive as well as pro-convulsant effects in vivo.[1],[2],[5]
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