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Tubermycin B is a bacterial metabolite that has been found in Pseudomonas and has antifungal and fungicidal activities.1,2 It is active against A. flavus, C. albicans, and T. rubrum (MICs = 64, 8, and 4 μg/ml, respectively), as well as the plant pathogenic fungi F. oxysporum and R. solani (MICs = 125 and 32 μg/ml, respectively).1 Tubermycin B (10-500 μg/ml) prevents the development of foliar anthracnose lesions in cucumber plants infected with the plant pathogenic fungus C. orbiculare.2 Formulations containing tubermycin B have been used as fungicides in agriculture.

1.Gorantla, J.N., Kumar, S.N., Nisha, G.V., et al.Purification and characterization of antifungal phenazines from a fluorescent Pseudomonas strain FPO4 against medically important fungiJ. Mycol. Med.24(3)185-192(2014) 2.Lee, J.Y., Moon, S.S., and Hwang, B.K.Isolation and in vitro and in vivo activity against Phytophthora capsici and Colletotrichum orbiculare of phenazine-1-carboxylic acid from Pseudomonas aeruginosa strain GC-B26Pest. Manag. Sci.59(8)872-882(2003)

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