化学性质:
规格 | 10 mg 50 mg |
CAS | 206 |
别名 | N/A |
化学名 | N/A |
分子式 | C18H16BCl3N2O2 |
分子量 | 409.5 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).
Baldwin et al (2017) Boron-based inhibitors of the NLRP3 inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355.
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