Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl estCS-01Y77837

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一、概述：

化学性质：

规格	10mM*1mLinDMSO 50mg
CAS	2150-43-8
别名	N/A
化学名	N/A
分子式	C8H8O4
分子量	168.15
溶解度	DMSO : ≥ 100 mg/mL (594.71 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) is a major metabolite of antioxidant polyphenols found in green tea. Antioxidant and anti-inflammatory effect[1].

Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) alleviates the toxic effects of F- via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells[1].

Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F- accumulation and oxidative stress. It prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2[2].

[1]. Ameeramja J, et al. Protocatechuic acid methyl ester ameliorates fluoride toxicity in A549 cells. Food Chem Toxicol. 2017 Nov;109(Pt 2):941-950. [2]. Ameeramja J, et al. Protocatechuic acid methyl ester modulates fluoride induced pulmonary toxicity in rats. Food Chem Toxicol. 2018 Aug;118:235-244..
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标签：Methyl 3 4-dihydroxybenzoate (Protocatechuic acid

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抑制剂 > 免疫学/炎症 > Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl est

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