IACS-8803 disodiumCS-01Y77833_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	1 mg 5 mg
CAS	2243079-36-7
别名	N/A
化学名	N/A
分子式	C20H23FN10Na2O9P2S2
分子量	738.51
溶解度	H2O : 56.67 mg/mL (76.74 mM; Need ultrasonic)
储存条件	Store at -20°C, stored under nitrogen
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1].

IACS-8803 (10 μg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1].

[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640..
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2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

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