化学性质:
规格 | 1 mg 5 mg |
CAS | 2243079-36-7 |
别名 | N/A |
化学名 | N/A |
分子式 | C20H23FN10Na2O9P2S2 |
分子量 | 738.51 |
溶解度 | H2O : 56.67 mg/mL (76.74 mM; Need ultrasonic) |
储存条件 | Store at -20°C, stored under nitrogen |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1].
IACS-8803 (10 μg; intra-tumoral injection) shows superior antitumor activity in mice bearing bilateral B16-OVA melanomas[1].
[1]. Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640..
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