化学性质:
规格 | 10mg 25mg 50mg 100mg |
CAS | N/A |
别名 | N/A |
化学名 | Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin pentachloride |
分子式 | C44H36MnN8 ? 5Cl |
分子量 | 909 |
溶解度 | Soluble at concentration of at least 50mg/mL in 0.1 M Tris-HCI buffer (1 mM EDTA, pH 9.0), and 4mg/mL in PBS (pH 7.2) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, respectively. Mn(III)TMPyP protected and enhanced the growth of SOD null E. coli with a doubling time of 60 minutes (as compared to 240 minutes of the control) at 25 µM.
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标签:Mn(III)TMPyP
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