化学性质:
规格 | 50 mg 100 mg 250 mg 500 mg |
CAS | 88763-76-2 |
别名 | N/A |
化学名 | N/A |
分子式 | C5H10N2O |
分子量 | 114.1 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
D-Ornithine lactam is a building block.1,2 It has been used in the synthesis of hepatitis C virus (HCV) non-structural protein 5B (NS5B) inhibitors, as well as αVβ3 integrin receptor antagonists.
1.Li, P., Dorsch, W., Lauffer, D.J., et al.Discovery of novel allosteric HCV NS5B inhibitors. 2. Lactam-containing thiophene carboxylatesACS Med. Chem. Lett.8(2)251-255(2017) 2.Kubota, D., Ishikawa, M., Ishikawa, M., et al.Tricyclic pharmacophore-based molecules as novel integrin ɑvβ3 antagonists. Part IV: Preliminary control of ɑvβ3 selectivity by meta-oriented substitutionBioorg. Med. Chem.14(12)4158-4181(2006)
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