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Anacardic acid triene is a polyunsaturated form of anacardic acid that has been found in cashew nut shell liquid. It inhibits soybean lipoxygenase-1 (IC50 = 60 μM in an enzyme assay) and inhibits superoxide production by xanthine oxidase by 82% when used at a concentration of 88 μM. Anacardic acid triene is active against S. mutans and S. aureus, including the methicillin-resistant S. aureus (MRSA) strain ATCC 33591 (MICs = 1.56, 6.25, and 6.25 μg/ml, respectively). It also inhibits NADH oxidase (IC50 = 1.3 μg/ml), an enzyme involved in bacterial respiration. Anacardic acid triene is molluscicidal, inducing toxicity in B. glabrata (LC50 = 0.35 ppm), but is inactive against S. mansoni parasites.

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