化学性质:
规格 | 1 mg 5 mg 10 mg 25 mg 50 mg |
CAS | 1414976-20-7 |
别名 | N/A |
化学名 | N/A |
分子式 | C36H47ClN8O3 |
分子量 | 675.26 |
溶解度 | H2O : 50 mg/mL (74.05 mM; Need ultrasonic)|DMSO : 50 mg/mL (74.05 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Vazegepant (BHV-3500) hydrochloride is a highly affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). Vazegepant hydrochloride is the first intranasal gepant for migraine. Vazegepant hydrochloride may be helpful in effective management of COVID-19 associated pulmonary inflammation[1][2][3].
[1]. Moreno-Ajona D, et al. Gepants, calcitonin-gene-related peptide receptor antagonists: what could be their role in migraine treatment•. Curr Opin Neurol. 2020;33(3):309-315.
[2]. Mehta PP, et al. Novel and Evolving Therapies for COVID-19 Related Pulmonary Complications. Am J Med Sci. 2021;361(5):557-566.
[3]. Moreno-Ajona D, PÉrez-RodrÍguez A, Goadsby PJ. Gepants, calcitonin-gene-related peptide receptor antagonists: what could be their role in migraine treatment•. Curr Opin Neurol. 2020;33(3):309-315.
特别提醒:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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