上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 10mg 50mg 100mg |
| CAS | 3106-85-2 |
| 别名 | N/A |
| 化学名 | (S)-2-((R)-2-acetamido-3-carboxypropanamido)pentanedioic acid |
| 分子式 | C11H16N2O8 |
| 分子量 | 304.26 |
| 溶解度 | <30.43mg/ml in H2O |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
Spaglumic Acid is a neuropeptide found in millimolar concentrations in brain.
Spaglumic Acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. The levels of Spaglumic Acid and the activity of carboxypeptidase II are altered in a regionally specific fashion in several neuropsychiatric disorders[1].
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