化学性质:
规格 | 1mg 5mg 10mg |
CAS | 1975976-24-9 |
别名 | N/A |
化学名 | N/A |
分子式 | C33H50O4 |
分子量 | 510.7 |
溶解度 | DMF: 30mg/mL,DMSO: 20mg/mL,Ethanol: 30mg/mL,Ethanol:PBS (pH 7.2) (1:40): 0.02mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Oleanolic acid acrylate (OAA) is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A and a derivative of oleanolic acid .1 It acts as an agonist at the 5-HT1A receptor in mouse hippocampal homogenates in a [35S]GTPγS binding assay (EC50 = 0.79 μM). It is also a selective inhibitor of MAO-A over MAO-B (IC50s = 48.8 μM and >100 μM, respectively). In mice, OAA (10 mg/kg) reduces immobility in the forced swim test and increases the number of crossings and time spent at the center in the open field test, indicating anti-depressant-like and anxiolytic activities
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