Neuromedin NCS-01Y76867_上海莼试生物技术有限公司

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化学性质：

规格	5mg 10mM*1mL in Water 25mg 50mg 100mg
CAS	92169-45-4
别名	N/A
化学名	N/A
分子式	C38H63N7O8
分子量	745.95
溶解度	H2O: 50 mg/mL (67.03 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Dopamine D2 receptor[1].

Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases[1]. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin[2].

[1]. Li XM, et al. Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neurosci Lett. 1993 Jun 11;155(2):121-4. [2]. Checler F, et al. Neuromedin N: high affinity interaction with brain neurotensin receptors and rapid inactivation by brain synaptic peptidases. Eur J Pharmacol. 1986 Jul 31;126(3):239-44.

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标签：Neuromedin N

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