化学性质:
规格 | 25 mg 50 mg 100 mg 250 mg |
CAS | 1 |
别名 | N/A |
化学名 | N/A |
分子式 | C8H14N4O2 |
分子量 | 198.2 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Mebicar is an anxiolytic with antiepileptic activity.1,2 In vivo, mebicar (10 mg/kg) reduces anxiety-like behavior and decreases stress-induced increases in serum corticosterone and pro-inflammatory cytokine levels in a mouse model of intermittent unpredictable stress.1 It inhibits epileptic activity in a rat model of penicillin-induced focal epilepsy.2
1.Kim, C.Y., Kim, Y.G., Sin, S.J., et al.Preventive effect of mebicar and ginsenoside Rg1 on neurobehavioral and immunological disruptions caused by intermittent unpredictable stress in miceNeuroImmunoModulation25(1)49-58(2018) 2.Rekhtman, M.B., Torshin, V.I., and Darinski?, N.V.Effect of mebikar on focal epileptic activityBiull. Eksp. Biol. Med.91(2)178-181(1981)
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标签:Mebicar
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