化学性质:
规格 | 5 mg |
CAS | 114-90-9 |
别名 | N/A |
化学名 | N/A |
分子式 | C14H16Cl2N4O3 |
分子量 | 359.21 |
溶解度 | N/A |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Obidoxime dichloride is a non-full spectrum oxime agent and can be used as an antidote for organophosphate nerve agent poisoning. Obidoxime dichloride reactivates sarin-inhibited acetylcholinesterase (AChE) and reduces acute toxicity of sarin-evaluated[1].
Obidoxime dichloride (intramuscular injection; 10 mg/kg; after 60 mins) exhibits a LD50 of 57.7 mg/kg after administration of sarin, and it reduces reduces acute toxicity of sarin was evaluated[1].
[1]. Kassa J,et al. A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice.Toxicol Mech Methods. 2015 Mar;25(3):229-33.
特别提醒:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
联系人:高小姐
手 机:13585831301
Q Q:3004967995
座 机:021-59541103
传 真:021-60443211
地 址:上海嘉定区嘉罗公路1661