化学性质:
规格 | 10mM (in 1mL DMSO) 50mg |
CAS | 969-33-5 |
别名 |
|
化学名 | 4-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-1-methylpiperidine;hydrochloride |
分子式 | C21H22ClN |
分子量 | 323.86 |
溶解度 | ≥ 14.15mg/mL in DMSO |
储存条件 | Desiccate at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Cyproheptadine hydrochloride is an antagonist of serotonin receptor [1].
Cyproheptadine is a serotonin and histamine antagonist as well as an antimuscarinic reagent. It is used to treat for postgastrectomy-dumping syndrome, pruritic dermatoses, migraine, anorexia, and pituitary-dependent Cushing's syndrome. The major urinary product of cyproheptadine is cyproheptadine glucuronide, a quaternary ammonium compound. Cyproheptadine has some side effects including sedation, drowsiness, hypotension, tachycardia and blood dyscrasias. As a 5-HT2A receptor antagonist, cyproheptadine is found to reverse serotonin-enhanced ADP-induced platelet aggregation in vitro and ex vivo suggesting its antiplatelet and thromboprotective effects. [1, 2]
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