Amyloid β-Peptide (10-20) (human)CS-01Y75757_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	1mg 5mg 10mg 25mg
CAS	152286-31-2
别名	Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe
化学名	Amyloid β-Peptide (10-20) (human)
分子式	C71H99N17O16
分子量	1446.67
溶解度	≥ 144.7mg/mL in DMSO
储存条件	Desiccate at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

The amyloid β-peptide (Aβ) has a central role in initiating neurodegeneration in Alzheimer disease (AD) 1. It is widely believed to be an incidental catabolic byproduct of the amyloid β protein precursor (APP) with no normal physiological function.2

Aβ has been shown to be a ligand for a number of different receptors and other molecules3-5. It is transported between tissues and across the blood brain barrierby complex trafficking pathways6. Aβ is modulated in response to a variety of environmental stressors and is able to induce pro-inflammatory activities7.

Soluble amyloid β-peptide fragment that is a substrate for gelatinase A/type IV collagenase/MMP-2 and APP secretase; cleaved between Lys16 and Leu17.

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标签：Amyloid β-Peptide (10-20) (human)

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