化学性质:
规格 | 5 mg 10 mg 25 mg 50 mg 100 mg |
CAS | 1609580-97-3 |
别名 | N/A |
化学名 | N/A |
分子式 | C21H16N4O2 |
分子量 | 356.38 |
溶解度 | DMSO : 25 mg/mL (70.15 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
(Rac)-PF-06256142 is the less effective enantiomer of PF-06256142 . (Rac)-PF-06256142 is an agonist of D1 receptor, with an EC50 of 107 nM. (Rac)-PF-06256142 can be used for the research of schizophrenia and Parkinson’s disease[1].
[1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018 Nov 15.
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