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抑制剂 > 神经科学 > 5α,6α-epoxy Cholestanol
产品名称:
5α,6α-epoxy Cholestanol
型号:
CS-01Y75653
生产地址
进口、国产
产品价格
电议
产品简介
质量保证、价格优惠
产品详情

一、概述:

化学性质:                                                                                                             

规格

25mg 50mg 100mg 250mg

CAS

1250-95-9

别名

NSC 18176

化学名

(3β,5α,6α)-5,6-epoxy-cholestan-3-ol

分子式

C27H46O2

分子量

402.7

溶解度

20mg/ml in ethanol; 0.1mg/ml in DMSO; 2mg/ml in dimethyl formamide

储存条件

Store at -20°C

General tips

For obtaining a higher solubility , please warm the tube at 37 and shake it in the ultrasonic bath for a while.

Shipping Condition

Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

 

产品描述:                                                                                                            

5α,6α-epoxy Cholestanol is an oxysterol and a metabolite of cholesterol produced by oxidation.[1]  5α,6α-epoxy Cholestanol accumulates in MCF-7 breast cancer cells in a reactive oxygen species-dependent manner following tamoxifen and PBPE application and induces triacylglycerol biosynthesis by binding to liver x receptor β (LXRβ). [2] 5α,6α-epoxy Cholestanol levels are increased in rat aorta and mesenteric artery following orchidectomy, an effect that can be prevented by a DHA-supplemented diet.[1]  Levels are also increased in post-mortem frontal and occipital cortex of patients with Alzheimer’s disease. [3]

特别提醒:                                                                                                              

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。

标签: 6α-epoxy Cholestanol 

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