上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 1mg |
| CAS | 77058-74-3 |
| 别名 | 24(S)-24,25-EC |
| 化学名 | (3β,24S)-24,25-epoxy-cholest-5-en-3-ol |
| 分子式 | C27H44O2 |
| 分子量 | 400.6 |
| 溶解度 | Soluble in ethanol |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain. [1] It activates liver X receptors (LXRs) in the developing ventral midbrain to induce stem cell differentiation into dopaminergic neurons. 24(S),25-epoxy Cholesterol inhibits IL-6 production and degranulation of bone marrow-derived murine mast cells that express LXRβ.[2] It inhibits the conversion of demosterol to cholesterol by 3β-hydroxysterol δ24-reductase (DHCR24/Seladin-1) in CHO-7 and SRD-1 cells when used at a concentration of 2.5 μM. [3]
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