3-hydroxy-DL-KynurenineCS-01Y75606_上海莼试生物技术有限公司

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一、概述：

化学性质：

规格	10mg 25mg 50mg 100mg
CAS	484-78-6
别名	DL-3-Hydroxykynurenine
化学名	α,2-diamino-3-hydroxy-γ-oxo-benzenebutanoic acid
分子式	C10H12N2O4
分子量	224.2
溶解度	DMF: 0.5 mg/ml,DMSO: 1 mg/ml,Ethanol: 2 mg/ml,PBS (pH 7.2): 0.5 mg/ml
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

3-hydroxy-DL-Kynurenine is an active metabolite of tryptophan.1,2,3 It inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%, respectively, when used at a concentration of 100 μM.1 3-hydroxy-DL-Kynurenine is active against methicillin-resistant S. aureus (MRSA), S. epidermidis, vancomycin-resistant E. faecalis (VRE), E. coli, multidrug-resistant P. aeruginosa (MDRP), and C. albicans (IC50s = 31.2, 39.2, 57.6, 24, 25.6, and 137.6 μg/ml, respectively).2 It increases intracellular NAD+ levels and extracellular lactate dehydrogenase (LDH) activity in human neurons and astrocytes in a concentration-dependent manner.3

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标签：3-hydroxy-DL-Kynurenine

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