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Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the assay of sodium activity in blood, plasma, serum. etc.

Preincubation of the cells with the Na+ ionophore sodium ionophore III not only stimulated caffeate reduction, but completely abolished ATP synthesis. Addition of sodium ionophore III to cells in the steady state of caffeate reduction immediately dissipated the intracellular ATP level[1]. Lactate-sulfate grown cells are insensitive to the Na+ ionophore, ETH2120[2]. Sodium ionophore III ligand is a very effective receptor for the Eu3+ and Am3+ cations and can be considered as a potential extraction agent for nuclear iste treatment[3].

[1]. Imkamp F, et al. Chemiosmotic energy conservation with Na(+) as the coupling ion during hydrogen-dependent caffeate reduction by Acetobacterium woodii. J Bacteriol. 2002 Apr;184(7):1947-51. [2]. Wang L, et al. The role of Rnf in ion gradient formation in Desulfovibrio alaskensis. PeerJ. 2016 Apr 14;4:e1919. [3]. Makrlík, E, et al. Sodium Ionophore III as Very Effective Receptor for Trivalent Europium and Americium.J Solution Chem (2016) 45: 463.

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