化学性质:
规格 | 10 mg 50 mg |
CAS | 667427-75-0 |
别名 | N/A |
化学名 | N/A |
分子式 | C22H21NO4 |
分子量 | 363.41 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Selective TRPC6 positive allosteric modulator. Selectively activates TRPC6 over other TRP channels. Also activates TRPA1. Induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50 = 2.37 μM). Potentiates OAG (1-oleoyl-1-acetyl-sn-glycerol)-induced Ca2+ influx in human platelets, and enhances OAG-induced platelet aggregation.
H?fner et al (2019) Discovery and characterization of a positive allosteric modulator of transient receptor potential 我们
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