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Calcineurin substrate is a synthetic peptide that corresponds to the regulatory RII subunit of protein kinase A (PKA).1 It can be phosphorylated by PKA, and phosphorylated calcineurin substrate can be used to quantify calcineurin activity.

1.Namgaladze, D., Hofer, H.W., and Ullrich, V.Redox control of calcineurin by targeting the binuclear Fe2+-Zn2+ center at the enzyme active siteJ. Biol. Chem.277(8)5962-5969(2002)

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