化学性质:
规格 | 5mg 10mg 50mg 100mg |
CAS | 79055-68-8 |
别名 | D-2-Amino-5-Phosphonovaleric acid; D-APV |
化学名 | (R)-2-amino-5-phosphonopentanoic acid |
分子式 | C5H12NO5P |
分子量 | 197.13 |
溶解度 | PBS (pH 7.2): 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 μM) that competitively inhibits the glutamate binding site of NMDA receptors.[1] Whereas D-AP5 is the active (−)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity.1 AP5 has been widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.[2]
特别提醒:
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标签:D-AP5
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