上海莼试生物技术有限公司
上海莼试生物技术有限公司
化学性质：
| 规格 | 25μg 50μg 100μg 250μg |
| CAS | 213382-49-1 |
| 别名 | (±)5,6-DiHETrE |
| 化学名 | (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid |
| 分子式 | C20H34O4 |
| 分子量 | 338.5 |
| 溶解度 | 50mg/mL in DMSO, 50mg/mL in DMF |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述：
5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases. [1] 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-δ-lactone in solution. [2] 5(6)-DiHET activates large conductance calcium-activated potassium (BK) channels in smooth muscle cells from rat small coronary arteries. [3 It is a substrate for sheep seminal vesicle COX, producing 5,6-dihydroxy prostaglandin E1 and F1α metabolites in vitro. [4] 5(6)-DiHET levels decrease in plasma in a high-fat diet-induced rat model of hyperlipidemia.[5]
特别提醒：
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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