KN-92 phosphateCS-01Y74768_上海莼试生物技术有限公司

产品详情

一、概述：

化学性质：

规格	10mM (in 1mL DMSO) 5mg 10mg 50mg 200mg
CAS	1135280-28-2
别名	KN 92 phosphate;KN92 phosphate
化学名	(E)-N-(2-(((3-(4-chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide phosphate
分子式	C24H28ClN2O7PS
分子量	554.98
溶解度	≥ 25 mg/mL in DMSO, ≥ 43.1 mg/mL in EtOH with gentle warming
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

产品描述：

KN-92 phosphate is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). IC50 value:Target: KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell.

特别提醒：

1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2. 为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

标签：KN-92 phosphate

热卖产品最新促销最新推荐

抑制剂 > 膜转运蛋白/离子通道 > KN-92 phosphate

产品简介

产品详情

一、概述：

联系我们