化学性质:
规格 | 5 mg 10 mg 25 mg 50 mg 100 mg |
CAS | 222 |
别名 | N/A |
化学名 | N/A |
分子式 | C22H13F4N9 |
分子量 | 479.39 |
溶解度 | N/A |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1].
CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1].
[1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1
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