化学性质:
规格 | 5mg 10mg 50mg 100mg |
CAS | 56776-32-0 |
别名 | Stresam;HOE 36-801 |
化学名 | 6-chloro-N-ethyl-4-methyl-4-phenyl-3,1-benzoxazin-2-amine;hydrochloride |
分子式 | C17H18Cl2N2O |
分子量 | 337.24 |
溶解度 | ≥ 33.7 mg/mL in DMSO with gentle warming, ≥ 48.1 mg/mL in EtOH with gentle warming, ≥ 15.49 mg/mL in H2O with gentle warming |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Etifoxine hydrochloride (HOE 36-801 hydrochlorid) is potentiator of GABAA receptor function in cultured neurons. Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. IC50 value:Target: GABAA receptorEtifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration.
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