化学性质:
规格 | 1mg 5mg 10mg 20mg |
CAS | 194098-25-4 |
别名 | N/A |
化学名 | N/A |
分子式 | C17H19N3O2 |
分子量 | 297.35 |
溶解度 | DMSO: 41.67 mg/mL (140.14 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
CP-409092 is a GABA(A) partial agonist, used for the treatment of anxiety.
The pharmacokinetics of CP-409,092 following single intravenous and oral doses of 4 and 15 mg/kg, respectively, are characterized by high clearance of 169+ or -18 mL/min/kg, a volume of distribution of 8.99+ or -1.46 L/kg, and an oral bioavailability of 2.9%+ or -3%. Following oral administration of 100 mg/kg [14C]CP-409,092, the total recovery is 89.1%+ or -3.2% for male rats and 89.3%+ or -0.58% for female rats[1].
[1]. Kamel A, et al. Metabolism, pharmacokinetics and excretion of the GABA(A) receptor partial agonist [(14)C]CP-409,092 in rats. Xenobiotica. 2010 Jun;40(6):400-14.
特别提醒:
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标签:CP-409092
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