化学性质:
规格 | 10 mM * 1 mL in DMSO 5mg 10mg 25mg |
CAS | 1421866-48-9 |
别名 | N/A |
化学名 | N/A |
分子式 | C25H37N5O6 |
分子量 | 503.59 |
溶解度 | DMSO: 155 mg/mL (307.79 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
Apimostinel is an oral NMDA receptor partial agonist.
Apimostinel (NRX-1074) modulates the NMDA receptor in a similar fashion to GLYX-13, but has a synthetic modification to one of the amino acids, conferring increased potency and oral bioavailability[1].
In preclinical models the two compounds both appear to be highly efficacious across a number of CNS disorders[1].
[1]. Naurex's First Orally Active Molecule, NRX-1074, Demonstrates Statistically Significant Improvement in Depression Scores within 24 Hours in Phase 2 Study for Major Depressive Disorder. January 28, 2015.
特别提醒:
1. 本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2. 为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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