化学性质:
规格 | 5mg 10mg 50mg 100mg |
CAS | 1472624-85-3 |
别名 |
|
化学名 | [(1aS,2S,7aS)-1a,2,7,7a-tetrahydro-1H-cyclopropa[b]naphthalen-2-yl] 4-nitrobenzoate |
分子式 | C18H15NO4 |
分子量 | 309.32 |
溶解度 | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 0.5 mg/ml |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells.IC50 value: 11 nM ([14C]-lactate influx) [1]Target: MCT inhibitor; lactate transport inhibitor7ACC2 did not influence the prothrombin time which, together with a good in vitro ADME profile, supports the potential of this new family of compounds to act as anticancer drugs through inhibition of lactate flux.
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标签:7ACC2
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