化学性质:
规格 | 5mg 10mg 25mg 50mg |
CAS | 5 |
别名 | 8-bromo-cGMP, 8-bromo Guanosine 3’,5’-cyclic monophosphate |
化学名 | 8-bromo-guanosine cyclic 3',5'-(hydrogen phosphate), monosodium salt |
分子式 | C10H10BrN5NaO7P |
分子量 | 446.09 |
溶解度 | 10mg in PBS(pH7.2) |
储存条件 | Desiccate at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase.[1] At 1 µM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.[2]
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