化学性质:
规格 | 10mM*1mL in Water 50mg 100mg 200mg |
CAS | 1321546-70-6 |
别名 | N/A |
化学名 | N/A |
分子式 | C7H9ClFN3O4 |
分子量 | 253.62 |
溶解度 | H2O: 6.67 mg/mL (26.30 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific AMPAR agonist.
[1]. Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21. [2]. Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41. [3]. Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82.
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