化学性质:
规格 | 10mM (in 1mL DMSO) 10mg 50mg |
CAS | 448895-37-2 |
别名 |
|
化学名 | 1,3-bis(2-hydroxy-5-(trifluoromethyl)phenyl)urea |
分子式 | C15H10F6N2O3 |
分子量 | 380.24 |
溶解度 | ≥ 13.05mg/mL in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice |
产品描述:
NS1643 is a partial agonist of human ether-a-go-go-related gene (hERG) K(+) channels with an EC50 of 10.5 μM. NS1643 has distinct effects on erg2 (Kv11.2) currents by reducing channel inactivation especially at high concentrations[1]. NS1643 increases the repolarization reserve and exhibits an interesting new antiarrhythmic approach[2].
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